Submitted: 01 Feb 2017
Accepted: 06 Mar 2017
First published online: 18 Mar 2017
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Int J Basic Sci Med. 2017;2(1):29-32.
doi: 10.15171/ijbsm.2017.07
  Abstract View: 140
  PDF Download: 259
  Full Text View: 89

Original article

The Effects of Combined Training on OxidativeStress and Antioxidant Defense Indicators

Reza Delavar 1 * , Mehdi Mogharnasi 2, Nazanin Khoobkhahi 3

1 Assistant Professor, Department of Sport Sciences, Faculty of Education and Psychology, University of Sistan and Baluchestan, Zahedan, Iran
2 Associate Professor, Department of Sports Physiology, Faculty of Sport Sciences, University of Birjand, Birjand, Iran
3 MSc Student, Department of Sport Sciences, Faculty of Education and Psychology, University of Sistan and Baluchestan, Zahedan, Iran


Introduction: Physical activity and exercise due to increased cellular oxidative process lead to increased free-radical production and reactive oxygen species. "Oxidative stress" is defined as the disturbed balance between oxidative and antioxidative indicators in favor of oxidative species.

Methods: In this semi-experimental study, 23 sedentary boys volunteered to participate. They were randomly assigned to 2 groups of training (n = 13) and control (n = 10). The combined trainings included endurance running with 60% to 80% of maximum heart rate and resistance weight training with 40% to 50% and one repetition maximum intensity. Blood samples were taken from the subjects’ forearm vein, 24 hours before and 48 hours after the last training session in a fasting state. Paired and independent t tests were used to locate the inner-group and inter-group changes respectively. Data were analyzed using SPSS version 20. A P <0.01 was considered significant.

Results: Malondialdehyde (MDA) level as a marker of oxidative stress in the exercise group decreased significantly after 24 sessions of exercise (P = 0.015), while the index of total antioxidant capacity (TAC) significantly increased in the exercise group (P = 0.021). There was no significant difference in the 2 indexes in the control group (P < 0.05).

Conclusion: The present study suggests that combined training provides a good balance between indicators of oxidative stress and antioxidant defense among sedentary boys and this would prevent the overproduction of free radicals.

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