Submitted: 16 May 2017
Accepted: 17 Jun 2017
First published online: 30 Jun 2017
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Int J Basic Sci Med. 2017;2(2):95-100.
doi: 10.15171/ijbsm.2017.18
  Abstract View: 337
  PDF Download: 456
  Full Text View: 286

Original article

Comparison of the Effects of Aerobic Exercise on Pulmonary Function and Levels of Inflammatory Mediators in Men With Type 2 Diabetes

Hossein Saki 1, Shiva Shahrokhian 2, Vahid Taeid 3, Mahmood Amani 1, Hamid Talebifard 4, Mojtaba Delaramnasab 5 *

1 MSc in Exercise Physiology, Department of Physical Education and Sports Science, Bu-Ali Sina University, Hamedan, Iran
2 MSc in Exercise Physiology, Department of Physical Education and Sports Science, Shahid Chamran University, Ahvaz, Iran
3 MSc in Exercise Physiology, Department of Physical Education and Sports Science, Shahid Rajaee Teacher Training University, Tehran, Iran
4 MSc in Exercise Physiology, Department of Physical Education and Sports Science, Abadan Branch, Islamic Azad University, Iran
5 Clinical Research Development Unit, Amir-Al-Momenin Hospital, Zabol University of Medical Sciences, Zabol, Iran
*Correspondence to Mojtaba Delaramnasab, Tel: +985432232166 Email:


Introduction: Insufficient pulmonary function is a complication of type 2 diabetes coordinating with poor blood sugar management and promoting an inflammatory condition. Our objective was to assess the effects of consistent aerobic exercises on pulmonary function and levels of some inflammatory cytokines in males with type 2 diabetes.

Methods: In the present semi-experimental study, 20 men with type 2 diabetes were selected using purposive sampling method. The recruited patients were randomly assigned into one of the aerobic exercise or control groups. The exercises continued for 8 weeks, 3 sessions per week, and each session consisted 45-60 minutes of aerobic exercise with intensity of 50%-70% heart rate reserve (HRR). Spirometry and hematologic parameters were both measured at 48 hours prior and 72 hours subsequent to the intervention. Statistical analysis was performed using SPSS v. 22.0 statistical software. Independent and paired sample t test were used for inferential analysis with P≤0.05 regarded as statistically significant.

Results: A significant reduction was observed in serum levels of fasting blood sugar (FBS), glycosylated hemoglobin (HbA1c), C-reactive protein (CRP), and interleukin 6 (IL-6) in aerobic exercise group (P<0.05). On the other hand, forced vital capacity (FVC), and forced expiratory volume (FEV1) levels showed a significant elevation in the experimental group relative to the control.

Conclusion: Considering our findings, it seems that aerobic exercise can improve pulmonary function in type 2 diabetes patients. This may be in some levels mediated by stabilizing blood glucose levels and subsiding systemic inflammatory condition in these patients.

Please cite this article as follows: Saki H, Shahrokhian S, Taeid V, Amani M, Talebifard H, Delaramnasab M. Comparison of the effects of aerobic exercise on pulmonary function and levels of inflammatory mediators in men with type 2 diabetes. Int J Basic Sci Med. 2017;2(2):95- 100. doi:10.15171/ijbms.2017.18.
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