Submitted: 27 Nov 2017
Revised: 16 Feb 2018
Accepted: 08 Mar 2018
First published online: 03 Oct 2018
EndNote EndNote

(Enw Format - Win & Mac)

BibTeX BibTeX

(Bib Format - Win & Mac)

Bookends Bookends

(Ris Format - Mac only)

EasyBib EasyBib

(Ris Format - Win & Mac)

Medlars Medlars

(Txt Format - Win & Mac)

Mendeley Web Mendeley Web
Mendeley Mendeley

(Ris Format - Win & Mac)

Papers Papers

(Ris Format - Win & Mac)

ProCite ProCite

(Ris Format - Win & Mac)

Reference Manager Reference Manager

(Ris Format - Win only)

Refworks Refworks

(Refworks Format - Win & Mac)

Zotero Zotero

(Ris Format - FireFox Plugin)

Int J Basic Sci Med. 2018;3(3):109-113.
doi: 10.15171/ijbsm.2018.20
  Abstract View: 92
  PDF Download: 109

Original article

Acute and Recovery Changes of TNF-α and IL-1β in Response to Aerobic Exercise in Smokers and Non-smokers

MohammadAli Seyed Hoseini 1, Mojtaba Eizadi 2 * ORCiD, Ashraf Amini 3, Zahra Mirakhori 3

1 Department of Physical Education and Sport Sciences, Parand Branch, Islamic Azad University, Tehran, Iran
2 Department of Exercise Physiology, Saveh Branch, Islamic Azad University, Saveh, Iran
3 Department of Physical Education and Sport Sciences, Amirkabir University of Technology, Tehran, Iran


Introduction: Recent evidence has shown that acute exercise modulates the immune response in healthy individuals, although the effect on smokers has not drawn much attention. This study examined acute and post exercise inflammatory responses in smokers and nonsmokers to moderate aerobic exercise. Methods: For this purpose, Fifteen recreationally sedentary male smokers and 15 nonsmokers matched for age (35.5 ± 5.8 years) and BMI(31.30 ± 4.5 kg/m2) were familiarized and underwent aerobic exercise testing involved 40 min running on flat surface with no slope at 70(%) of maximal heart rate. Venous blood was obtained pre-exercise (baseline), 0, 60 min and 24 hours for analysis of tumor necrosis factor-alpha (TNF-α), and interleukin-1 beta (IL-1β) of 2 groups. Experimental data were analyzed by one-way analysis of variance with repeated measures in each group. Results: No differences existed between groups for baseline IL-1B between 2 groups but serum TNF-α was higher in smokers. Aerobic exercise test results a significant decrease in serum TNF-α at 0, 60 min and 24 hours compared baseline in smokers but not in non-smokers. Serum IL-1βremained unchanged at all blood samples after exercise test in both groups. Conclusion: All together, based on acute and recovery response of TNF-α to exercise, it seems that a moderate aerobic exercise has beneficial effects on inflammatory profile in smokers.
First name
Last name
Email address
Security code

Article Viewed: 92

Your browser does not support the canvas element.

PDF Downloaded: 109

Your browser does not support the canvas element.