Submitted: 11 Nov 2019
Accepted: 25 Nov 2020
First published online: 25 Nov 2020
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Int J Basic Sci Med. 2020;5(3):114-117.
doi: 10.34172/ijbsm.2020.20
  Abstract View: 22
  PDF Download: 22

Original article

Platelet Count Applicability in Predicting the Degree of ST-Segment Depression and Coronary Flow Rate in Acute Myocardial Infarction Patients

Roghaiyeh Afsargharehbagh 1 * ORCiD, Kamal Khademvatani 2, Tohid Yahyapoor 2, Aliakbar Nasiri 3, Mahmood Moosazadeh 4, Motahareh Kheradmand 5, Mahdi Afshari 6, MirHossein Seyed-Mohammadzad 2 *

1 Department of Interventional Cardiology, Shohada Hospital, Urmia University of Medical Sciences, Urmia, Iran
2 School of Medicine, Urmia University of Medical Sciences, Urmia, Iran
3 Department of Anesthesiology, Urmia University of Medical Sciences, Urmia, Iran
4 Health Sciences Research Centre, Addiction Institute, Mazandaran University of Medical Science, Sari, Iran
5 Health Sciences Research Center, School of Health, Mazandaran University of Medical Sciences, Sari, Iran
6 Department of Community Medicine, Zabol University of Medical Sciences, Zabol, Iran


Introduction: It is still unclear whether platelet count can predict the outcomes of acute myocardial infarction. In this study, we assessed the relationship between the initial platelet count on the degree of ST-segment depression and coronary flow rate among patients with MI who underwent percutaneous coronary intervention (PCI). Methods: In this study, a total of 218 patients suffering from MI, who underwent primary PCI during 2016-2017 (Seyed-Shohada hospital, Urmia, Iran) were selected by consensus method. Demographic information and past medical history such as diabetes mellitus (DM), cigarette smoking, using Integrilin, and door-to-balloon (DTB) time were recorded. All patients were investigated in terms of cell blood count. Serial electrocardiogram (ECG) was also performed and the degree of ST-segment elevation was measured. Results: The mean (SD) age of participants was 58.67 (11.44) years. The initial platelet count was similar between patients with and without improvement in the ST-segment (P = 0.275). There was no significant difference regarding thrombolysis in myocardial infarction (TIMI) between patients with and without improved ST-segment (P = 0.380). Conclusion: According to our results, the initial platelet count in patients who underwent angioplasty was not associated with coronary flow and echocardiographic responses to treatment.
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