Ali Bazi 1,2 *
1 Clinical Research Development Unit, Amir-Al-Momenin Hospital, Zabol University of Medical Sciences, Zabol, Iran
2 Pediatric Gastroenterology and Digestive Diseases Research Center, Zabol University of Medical Sciences, Zabol, Iran
Abstract
Role of immune system in diabetes mellitus (DM) has been emerged for a long time. Since then, the majority of focus has been toward the role of adaptive immunity, while little thoughts credited a role for innate immunity in this process. By the emerging role of innate immunity in DM pathogenesis, especially toll-like receptors (TLRs) superfamily, it is expected that therapeutic approaches target these components in future of pharmaceutical research in diabetes.