Abstract
Introduction: Insufficient pulmonary function is a complication of type 2 diabetes coordinating
with poor blood sugar management and promoting an inflammatory condition. Our objective
was to assess the effects of consistent aerobic exercises on pulmonary function and levels of
some inflammatory cytokines in males with type 2 diabetes.
Methods: In the present semi-experimental study, 20 men with type 2 diabetes were selected
using purposive sampling method. The recruited patients were randomly assigned into one of
the aerobic exercise or control groups. The exercises continued for 8 weeks, 3 sessions per
week, and each session consisted 45-60 minutes of aerobic exercise with intensity of 50%-70%
heart rate reserve (HRR). Spirometry and hematologic parameters were both measured at 48
hours prior and 72 hours subsequent to the intervention. Statistical analysis was performed using
SPSS v. 22.0 statistical software. Independent and paired sample t test were used for inferential
analysis with P≤0.05 regarded as statistically significant.
Results: A significant reduction was observed in serum levels of fasting blood sugar (FBS),
glycosylated hemoglobin (HbA1c), C-reactive protein (CRP), and interleukin 6 (IL-6) in aerobic
exercise group (P<0.05). On the other hand, forced vital capacity (FVC), and forced expiratory
volume (FEV1) levels showed a significant elevation in the experimental group relative to the
control.
Conclusion: Considering our findings, it seems that aerobic exercise can improve pulmonary
function in type 2 diabetes patients. This may be in some levels mediated by stabilizing blood
glucose levels and subsiding systemic inflammatory condition in these patients.