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Submitted: 28 Jan 2023
Revision: 05 Mar 2023
Accepted: 07 Mar 2023
ePublished: 29 Jun 2023
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Int J Basic Sci Med. 2023;8: 69-76.
doi: 10.34172/ijbsm.28627
  Abstract View: 219
  PDF Download: 146

Review Article

An Overview of the ACE2 Receptor as the Main Coronavirus Keyword

Manijeh Yousefimoghadam 1 ORCID logo, Maryam Sadat Mirenayat 2,3 ORCID logo, Mahdi Heaidari 4, Reyhaneh Zahiri 2,3, Seyed Bashir Mirtajani 5 ORCID logo, Fatemeh Yassari 2 ORCID logo, Atefeh Fakharian 2,3* ORCID logo

1 Department of Anesthesiologist, School of Medicine, Sabzevar University of Medical Sciences, Sabzevar, Iran
2 Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NIRTLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran
3 Pulmonary Rehabilitation Research Center (PRRC), National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran
4 Department of Anesthesiology, School of Medicine, Clinical Immunology Research Center, Ali IbneAbitaleb Hospital, Zahedan University of Medical Sciences, Zahedan, Iran
5 Lung Transplantation Research Center (LTRC), National Research Institute of Tuberculosis and Lung Diseases (NIRTLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran
*Corresponding Author: Atefeh Fakharian, Email: fakharian_2005@yahoo.com

Abstract

The epidemic caused by the spread of the infectious agent called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has posed a huge challenge to various communities around the world. The high prevalence and widespread infectivity of this virus indicated that despite the relentless efforts of various biological scientists to provide appropriate treatment or control of the disease, no definitive treatment has been reported successfully. Since the source of infection of this virus is an entry into the host cell through the specific angiotensin-converting enzyme-2 (ACE2) receptor, in the present study, we reviewed the ACE2 receptor and its role in SARS-COV-2 infection.
Keywords: SARS-COV-2, Angiotensin-converting enzyme 2, Spike protein

Please cite this article as follows: Yousefimoghadam M, Mirenayat MS, Heaidari M, Zahiri R, Mirtajani SB, Yassari F, et al. An overview of the ACE2 receptor as the main coronavirus keyword. Int J Basic Sci Med. 2023;8(2):69-76. doi:10.34172/ijbsm.28627.
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